I am currently searching and received an invitation to interview with a company that would require at least an hour plus commute. The company does have a location closer to my home. How should I respond?
If this is a just once commute, I suggest you to go ahead and have the interview. During it, ask about the possibility to work at the closer location, but without putting too much emphasis (don't let them think that it's a dealbreaker condition, even if it is).
You can reevaluate after the interview whether to accept or refuse an offer.