One week ago, I emailed an HR person (unfortunately, it was just a
jobs@....com address, I could not find out who the hiring manager actually was) with my resume and cover letter. I received an email back within 10 minutes, with a CC to someone I know to be a manager. They called my resume impressive and they appeared to value one very strong advantage I have over pretty much anybody else. They asked me if I was looking to work in location X or Y, and I was clear that I wanted to work in X, but traveling to Y occasionally wasn't going to be a problem.
Now a week has passed and I haven't heard anything else. I know the general rule is that for unsolicited applications, no news pretty much means bad news and that they'll contact me if they are interested. However, they have contacted me, but now that contact has died down. They may not be so interested anymore because I don't want to work in Y, but since we have had contact, I would expect that to be communicated to me.
I know it has only been a week, and I understand there could be a plethora of reasons why I haven't heard anything (sickness, busy, no interest, etc.), but my question is: do I contact them again, asking about the status of my application? If so, at what point would that be a reasonable thing to do?