Ultimately, it's a matter of what image the reader is going to get. Since you're concerned, but haven't disclosed what the name of this "spooky" domain name is, I can only assume that it's something that you feel could potentially be an issue. A general rule of thumb I've heard is that if you have to ask, it's probably not appropriate (as with most rules of thumb, it's far from an absolute, of course. Only Sith deal in absolutes). Probably, your best bet is to run it by a neutral third party, and see what their reaction is to your email address. That could include us if you're willing to share it.
As a more general thing, using your own domain name is considered classy, but if your domain name could leave a bad impression, of course, that kind of overrules it.
As regards your later edit, I would probably have a negative reaction to a domain name such as "CodingHorror.com". If I were not familiar with the site in question, it would look flippant at best, and unintentionally self-revealing at worst.