Yes and this can be indicated in your resume and in your cover letter.
If you are in the United States (and perhaps elsewhere, but United States for sure), additional schooling while doing full-time work can be considered a "conflict of interest" depending on the place of work and, depending on the place of work, it may be grounds for disciplinary action if they find that your schooling is interfering with your job and that you had never told them about it before.
On the one hand, disclosing at the get-go might discourage some potential employers from hiring you (understandably, because what if you lose sleep over exams and projects or homework and can't stay a little later to finish up work, etc). On the other hand, a potential employer might go, "Oh okay. Just make sure your work is your first priority," and even encourage you in your studies and be supportive or might ask you to join the workforce after you're done with school.
Whatever you do, though, since schooling (or another job) can be considered a "conflict of interest", it is probably best to disclose at the get-go re: resume and/or cover letter.