As part of my work-study, I used to work as an intern in the HR department of a major research laboratory. In a big organization, one important job of HR is to prevent illegal discrimination and to reverse discrimination when it could.
So for that initial phase, it doesn't really matter what the HR people think of your resume. When it comes down to it, it comes down to the hiring managers if you're not even getting those initial interviews.
The resumes sent down from hiring managers were automatically given a higher priority both in the database search results and in the stack of paper resumes that were sent back to a hiring manager for a particular job number. I know this, because I was one of the poor interns who had to scan hundreds of resumes all day into Resumix, set the flags, and double-check the important identifiers for scanning for errors.
The reason for this priority flag was simple. Hiring managers disliked the HR department so much already. We didn't need to give them any additional reason to hate us by thinking that we had lost any resume that they had personally forwarded to us.
So if you're not sending your resume to the hiring managers directly, then you're probably sabotaging yourself during this job hunt to a certain degree. It doesn't matter what your name might be. And you should do whatever research it takes to get the names of departments, department heads, and managers in the actual departments you want to work in.
This can be done through good old fashioned networking, linkedin, reading industry news/journals, etc. but if those approaches don't work, at the very least you actually need to pick up the phone and call that organization yourself and ask for that information. And if that one phone call doesn't work, you need to do it over and over again, until you eventually get the relevant manager's name, the actual nickname he goes by if any, and the exact name of the department he works for to make sure your resume doesn't get lost trying to reach him through inter-departmental office mail.