If you have been self employed for 5 years you are definitely in need of a whole new resume. Make one that would appeal to the employer for whichever job you're applying for.
I would definitely mention your graphic design experience since this is applicable in many unrelated fields as well. It shows an ability to work with software, prepare/plan and complete projects and other things.
You seem to be applying for very low level positions though, so quite possibly your resume is not as important as higher level jobs. In my experience these sorts of jobs are usually looking for young, inexperienced (cheap) workers.
However that's no reason to skimp on your resume, focus on anything that directly pertains to the job, and list all your other skills as further arrows in your arsenal without emphasising them.