One problem with "job hopping" (as stated in another answer) is the cost to an employer to seek out a good match for the company. That is a very practical statement for a more difficult, softer issue which can be summarized with this question from a prospective employer:
"Explain how I can have any confidence that you will stay employed with us despite our imperfections that you cannot possibly be aware of at this time?"
You demonstrate less and less tenacity or endurance for workplaces that might not suite your specific taste, lifestyle or whatever. You are not a perfect employee and you will not find a perfect employer.
An employee that "hops" from one job to another may have expectations out of line with reasonable employment, or simply too fickle to believe will be a good fit for any company. Regardless, an employer should become increasingly skeptical about any employee that cannot seem to stay with a job longer than they expect you to be there in order to be productive and a worthwhile placement for the company.
Even so, different industries, jobs and employers have different degrees of tolerance for "job hopping." I am not familiar with your specific industry or job, but generally contractors are hired in cases where the return on investment is less than a year.
It is probably in your best interest to not even look for a job for a while. Even if you get a "great offer" you may find yourself in the proverbial situation of jumping out of the frying pan and into the fire. Then what??
If you can tolerate where you are for a while, then you should probably do that if you are interested in employment. If you want to return to self-employment, take the time to focus on your businesses instead of job hunting. Alternatively, look for contracts instead of employment...
Of course, you sound like a risk-taker in general. You probably don't have the patience or desire to listen to advice like this - and the more of a risk-taker you are, the less this advice actually applies. Employment hinders those with the proper skills and disposition to be self-employed. In which case, continue you on as you are! And report back how the adventure goes!
You just added that you have a degenerative neurological disorder that will likely leave you bed-ridden in 6-10 years. First, I am sorry to hear about your circumstances. That is tragic and certainly does change the tone of the question. At first, I was going to suggest that you ask another question and then, up front, specifically include your unique circumstances.
However, employment is about finding a mutually beneficial arrangement. Any employer should be concerned about your attitude toward employment, although you may have certain legal protections given your medical condition.
Often employment costs are front loaded, meaning that your initial employment is a greater cost to the company than what they are paying you, and much more than you are returning to the company for your work. It is an investment by the company in you. In order for the arrangement to be mutually beneficial, they need to recoup their investment after you begin making a return greater than your cost, and for some time after that. This is why the duration of employment matters.
Neither your eagerness nor your condition justify that companies take a higher risk on you than anyone else that is eager to rise quickly in their field in general. Some potential employers may see you as highly motivated and value that more than others. Most will probably be concerned about their inability to deliver on your vision of a "great" employer leading you to abandon their company just as quickly as you have your recent previous employers.
Your current attitude does not give potential employers confidence. You cannot know, before accepting a job, that you will be satisfied with it. Your eagerness to "condense your career" is not assurance that you are a risk worth taking. It comes across more like you are trying to justify employment arrangements that are biased toward your personal gain with people that do not have motivation (monetary or emotional) to favor you over others.
You need to be able to explain and/or demonstrate how your condition and circumstances is to the benefit of any future employer. Your eagerness to achieve is an asset, but eagerness is not enough.
(And I feel compelled to mention that I am not trying to provide legal advice and I recognize that your condition is a tremendous emotional burden. I wish you the best in your endeavors and hope these comments help you.)