This kind of person thrives on the idea that you are uncomfortable with his behaviour, and confronting him simply confirms to him that he is getting a response.

Simply ignore it - if in the middle of the conversation or meeting, just continue as if the guy has not said anything at all. Otherwise, steer to a professional conversation.

This person will stop getting enjoyment out of your discomfort (or will simply present himself as a jerk in front everyone else), and you can move on.