I'll echo the other answers in saying "Could it? Yes. Will it? Who knows?".
The new information I'll provide is to say that, unless you are doing significant, important, related work to the job you are seeking, I would omit it from the resume. You are seeking a software development job; you explained your relationship to this website as mainly a content manager. Those are not related responsibilities, so I would omit it. Aside from the issue you raised, it also takes up space on your resume that could better be used for detailing other things related to the position you're seeking, to become more attractive to the employer.
That said, top tech companies have a way of finding these sorts of things out anyway (even if they're not told directly by the person) and firing people once they do. I feel like your problem may go deeper than simply this, and you may have to make a decision in the not-too-distant future between your friends and your job*. An alternate plan of action that you might want to consider in light of this would be to ignore the fact that some companies may find the content offensive, and to say "ok, I don't want to work for those types of companies anyway" and use this link on your resume as a screening tool: "I only want to be employed by companies which will look at this site and its content and decide that the content is not objectionable".
Another way to look at it is that, the story is 250 pages, and nobody who isn't actually looking is going to read a 250 page story to screen a job applicant, that sounds ridiculous to say out loud. So maybe don't even worry about it?
<*> If this choice is given to you, always choose your friends. Your friends are the people who will be by your side, through thick and thin, when you need them to help you out with whatever your life throws at you. Your company is a faceless, emotionless entity who will just as soon throw you out the door on your butt with nothing at the drop of a hat. I've seen too many times when people throw away their friends on a promise and a prayer and get burned by it, and the fallout is not pretty. Always choose your friends.